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This Concept Map, created with IHMC CmapTools, has information related to: Celiacs Disease, Maldigestion more bacterial breakdown of nutrients leading to increased sulfur production, IL-15 leads to increased expression of NK-G2D (a NK cell marker), diarrhea prompting Duodenal Biopsy, diarrhea prompting X-ray, Lee Acton has a Family History, Lee Acton presents with diarrhea, Tissue Transglutaminase which increases its immunogenicity, enterocytes leading to Atrophic Villi, Adaptive Immune System such that CD4+ T cells, Lee Acton presents with fatigue, upper small intestine responsible for Calcium absorption, B Cells which differentiate into Plasma Cells, Innate Immune System including macrophages, Chrohn's not transmural, Maternal Grandfather of Nutritional Deficiencies, Family History of Maternal Grandfather, HLA Class II molecules DQ2 or DQ8 on APCs leading to secretion of proinflammatory cytokines, Duodenal Biopsy demonstrating Extensive Intraepithelial Lymphocytosis, ulcerative colitis no ulceration of epithelium, Lee Acton presents with Lactose Intolerance